7F

Probability in health and insurance

Using probability and expected frequency to make real decisions: blood types and donor matching, reading medical test results with an expected-frequency table, and how insurers use claim rates to set premiums.

Probability isn't only about dice and raffles. Hospitals plan blood supplies with it. Doctors use it to explain what a test result really means. Insurers use it to decide what to charge you for car or contents insurance. The maths is the same as the last two sections: a probability from data, multiplied by a number of people. The skill is reading the situation carefully.

Blood types and donors

Every person's blood has a type made of two parts. The ABO group (O, A, B or AB) depends on which markers, called antigens, sit on the red cells: A, B, both, or neither. The Rh factor is positive (+) if the cells carry the RhD marker and negative (−) if not. A patient can safely receive red cells only if the donor's cells carry no marker the patient doesn't already have.

The table shows approximate percentages of each type among Australians, based on figures published by Australian Red Cross Lifeblood. They are rounded and vary a little between sources.

TypeO+O−A+A−B+B−AB+AB−
Approx. %4093178221
Example 1●●

A Lifeblood donor centre expects 2500 donors this month. (a) How many would you expect to be O−? (b) A patient has type A+. What is the probability that a randomly chosen donor can give red cells to this patient?

$2500 \times 0.09 = 225$ O− donors
9% of people are O−, so P(O−) = 0.09. Multiply by the number of donors for the expected frequency.
Compatible donors: O+, O−, A+, A−
An A+ patient has the A and RhD markers, so donor cells may carry A, RhD, both or neither. That allows O+, O−, A+ and A−.
$40\% + 9\% + 31\% + 7\% = 87\%$, so $P = 0.87$
These types don't overlap, so add their percentages.
InteractiveMatch a donor to a patient
Try this

Choose the patient's blood type. The donor types that can safely give red cells light up green, and the readouts give the probability and the expected number of matching donors.

Which patient type has the fewest matching donors? Which has the most? Set the slider to 300 donors and find how many would match a B+ patient.

What does a positive test really mean?

Medical tests aren't perfect. A test might correctly pick up $95\%$ of people who have a condition, but also wrongly flag $5\%$ of people who don't. When a condition is rare, those false alarms can outnumber the real cases. The clearest way to see this is to imagine a round number of people and fill in an expected-frequency table.

Example 2●●●

A condition affects $2\%$ of people. A screening test gives a positive result for $95\%$ of people who have it and for $5\%$ of people who don't. Imagine 1000 people are tested. Find the probability that a person with a positive result actually has the condition.

Have it: $1000 \times 0.02 = 20$. Don't have it: $1000 - 20 = 980$.
Start with the 1000 people and split them by whether they have the condition.
True positives: $20 \times 0.95 = 19$
Of the 20 with the condition, 95% test positive.
False positives: $980 \times 0.05 = 49$
Of the 980 without the condition, 5% wrongly test positive.
$P(\text{has it, given positive}) = \frac{19}{19 + 49} = \frac{19}{68} \approx 0.28$
'Given a positive result' means the 68 positives are the whole group. Only 19 of them really have it.
Test positiveTest negativeTotal
Has condition19120
No condition49931980
Total689321000

So only about 28 in every 100 positive results are real. This is why a positive screening test is usually followed by a second, more accurate test before anyone is diagnosed.

How insurers set premiums

An insurer can't know which customers will make a claim, but from years of data it knows the claim rate. It uses expected frequency to estimate the total it will pay out, then shares that cost across all customers.

Break-even premium
$$\text{break-even premium} = \frac{\text{expected number of claims} \times \text{average claim}}{\text{number of policies}} = P(\text{claim}) \times \text{average claim}$$
Example 3●●

Records show 3 claims per 1000 home contents policies each year, with an average claim of $\$15{,}000$. An insurer has 20{,}000 policies. Find the expected number of claims, the expected total payout, and the break-even premium per policy.

$\text{expected claims} = 20{,}000 \times 0.003 = 60$
3 claims per 1000 policies means P(claim) = 3/1000 = 0.003.
$\text{expected payout} = 60 \times \$15{,}000 = \$900{,}000$
Each claim costs 15 000 dollars on average.
$\text{premium} = \frac{\$900{,}000}{20{,}000} = \$45$
Share the expected payout equally across all policies.
The insurer must charge more than $\$45$ to make money.
The insurer also has wages, offices and profit to cover, so the real premium will be higher.

Your turn

A car insurer finds that $4\%$ of its policyholders make a claim each year, and the average claim is $\$6{,}500$. What is the break-even premium per policy?

Show the answer

$\text{break-even premium} = 0.04 \times \$6{,}500 = \$260$. Out of every 100 policies, 4 claims cost $4 \times \$6{,}500 = \$26{,}000$, and $\$26{,}000 \div 100 = \$260$.

Flashcards
Who can receive O− red cells?
Everyone. O− is the universal red-cell donor, but O− patients can receive only O−.
Expected-frequency table
Imagine 1000 people, split them by each percentage in turn, then read the probability from the right row or column.
Break-even premium
$P(\text{claim}) \times \text{average claim}$
Practice
  1. About $40\%$ of Australians have type O+ blood. How many of 2500 donors would you expect to be O+?

  2. About $1\%$ of Australians are AB−. How many of 400 donors would you expect to be AB−?

  3. A patient has type B−. Which donors can give them red cells?

  4. Using the table on this page, $59\%$ of donors can give red cells to a B+ patient. How many of 300 donors would you expect to be suitable?

  5. Which patient type can receive red cells from the largest group of donors?

  6. An insurer records 3 claims for every 1000 policies each year. How many claims should it expect from 20{,}000 policies?

  7. A car insurer finds $4\%$ of policies lead to a claim each year, with an average claim of $\$6{,}500$. Find the break-even premium in dollars.

  8. Why does an insurer charge more than the break-even premium?

  9. Exam style: A condition affects $2\%$ of people. A test gives a positive result for $5\%$ of people who do not have the condition. Out of 1000 people tested, how many would you expect to be false positives?

  10. Exam style: A condition affects $1\%$ of 10{,}000 people. A test is positive for $90\%$ of those with the condition and $8\%$ of those without it. Find, as a decimal to one decimal place, the probability that a person with a positive result has the condition.

Formula sheet